Novel Optics, Ningbo Yongxin Optics Co., Ltd.

NOS1000 Structured‑Light Optical‑Sectioning Microscope

The structured‑light optical‑sectioning microscope improves optical resolution via specialized illumination patterns to break the diffraction limit of conventional fluorescence microscopes. It enables fast, low‑phototoxicity 3D optical‑sectioning imaging, greatly suppressing out‑of‑focus fluorescence interference as well as autofluorescence from specimens and culture media. Sharper, more authentic sample images can be acquired to expand the possibilities of your research.

Overview

An All‑rounder for Fluorescence Imaging: Bring Stereoscopic Vision to Life‑Science Research

Observe ultra‑fine details with high resolution and high signal‑to‑noise ratio while retaining the acquisition efficiency of wide‑field imaging.

High‑Resolution Imaging
It achieves optical resolutions of 120 nm in XY and 200 nm along the Z‑axis. Out‑of‑stray‑light is effectively rejected for crisp visualization of microstructural details.

Video‑rate Imaging Speed
Delivering high‑resolution, sharp images, the NOS1000 supports high‑speed imaging up to 30 FPS. Clear, complete sample datasets can be acquired within extremely short exposure times. Its 30 fps video‑grade frame rate captures fast intracellular events such as protein transport and ion flow, ensuring you never miss critical biological moments.

Proven Nexcope Optical System

With eighty‑year‑long expertise in optics, Nexcope manufactures every objective lens with meticulous craftsmanship to deliver top‑tier clarity and comprehensive optical performance. Outstanding image quality is maintained across low‑ to high‑magnification ranges.

NIS‑series objectives feature high numerical aperture, long working distance and superior chromatic aberration correction. Multi‑layer coating and strict production standards deliver sharp, high‑fidelity images for both routine tasks and cutting‑edge research.

High‑Performance Microscopy Platform: NIB1000 Research‑Grade Inverted Microscope

The NIB1000 delivers powerful, flexible imaging workflows and builds a robust, highly‑expandable foundation for the NOS1000 system. Its 25 mm field‑of‑view design and high‑speed motorized controls ensure user‑friendly operation, ideal for large‑specimen and high‑throughput experiments.

High‑speed Motorized Control
Operational and switching speeds for objectives, filter blocks, XY stage and observation modules are greatly enhanced, letting researchers focus on observation and image acquisition. Joystick‑enabled stage manipulation delivers intuitive, responsive handling.

AFS for Stable, Reliable Imaging Results
The newly‑designed Adaptive Focus System (AFS) intelligently eliminates focus drift. Whether paired with high‑NA high‑magnification objectives or deployed with advanced imaging modalities including super‑resolution, confocal and optical sectioning, it consistently produces crisp, sharp images.

Live‑cell Incubation System
Purpose‑built for precise live‑cell imaging. It accurately regulates platform temperature and maintains constant temperature, humidity and CO₂ concentration inside culture dishes, generating optimal incubation conditions for long‑term experiments.

Comprehensive Software Platform for Powerful Analysis & Visualization: Nomis Pro X

Custom‑engineered by Nexcope, Nomis Pro X delivers highly integrated hardware control for core microscope functions, seamlessly merged with data‑analysis workflows. It constitutes an all‑in‑one experimental platform with outstanding performance and intuitive operation.

Boasting exceptional system integration and flexibility, it handles complex research scenarios and specialized experimental requirements. It streamlines workflows, freeing users from tedious manual microscopy operations so they can focus on scientific exploration and innovation.

High‑speed Hardware Control
Delivering exceptional operational convenience, it enables streamlined digital management and precise control of multiple motorized microscope components, including objective switching, focusing, condenser adjustment and fluorescence module toggling.

Multi‑dimensional Imaging & Image Display
Custom observation profiles can be saved. Combined X, Y, Z, λ, T scan modes are supported to accommodate diverse complex experimental scenarios.

Deconvolution
It performs deblurring for 2D images. Multiple deconvolution passes eliminate shot‑noise artifacts within confocal datasets. 3D deconvolution is also available for multi‑dimensional image stacks.

Powerful Application Expandability

Benefiting from tunable structured‑illumination technology and the flexible microscopy platform, the NOS1000 features remarkable expandability. Users can readily add accessories such as live‑cell incubation systems, super‑resolution modules and FRAP (Fluorescence Recovery After Photobleaching) experimental modules to satisfy diverse application demands.

It delivers comprehensive, efficient solutions for cell biology, molecular biology, biomedical research and other disciplines.